NEXT-GENERATION PROTEOMIC APPLICATIONS
Unbiased, proteome-wide, quantitative proteomics
- Wide variety of biological matrices, including cell lines, primary tissues, and biofluids (serum, plasma, csf)
- Drug target identification and specificity profiling
- Chemoproteomics
- Unbiased covalent inhibitor target profiling
- Target engagement
- Quantitative protein-protein interactions profiling (immunoaffinity purification, proximity labeling)
- Post-translational modifications
Technology
- Multiplexing with TMT™ 18-plex reagents
- PTMScan® Technology (phosphotyrosine, acetylation, ubiquitylation)
- Real-time search MS3 (TMT™) or DIA acquisition
- Orbitrap Lumos/Eclipse
- Orbitrap Exploris 480
- Orbitrap Astral
- Dedicated informatics pipeline for data analysis
Consistent, sensitive, and rapid quantification of biologically relevant targets
- Custom targeted assays
- Target engagement
- Absolute and relative quantification
- Reduced sample requirements and high-throughput sample analysis
Technology
- PRM or multiplexed (TMT™) assays
- Orbitrap Lumos/Eclipse/Exploris
- Orbtirap Astral
- End-to-end automated plate-based sample preparation
- Preferred vendors for isotopically heavy standards
Support services for proteome characterization
- Cell culture
- Proteome informatics
- Instruments as a Service
- LC-MS acquisition of customer prepared samples (hourly / weekly / monthly pricing)
- Expedited processing / data acquisition
Technology
- Scalable local and cloud computing
- Automated sample preparation
- BSL2 certification
Why IQ Proteomics
Proven expertise
Established in 2015, IQP’s leadership has a proteomics specific background and extensive training in proteomics, including a library of peer-reviewed publications. IQP has completed thousands of projects from nearly all of the world’s largest, to the newest, pharmaceutical and biotechnology companies.
Dedicated facilities
Located just outside of Boston, MA, IQP occupies a purpose-built LC-MS laboratory for sample storage, preparation, LC-MS analysis, and cell culture. All work is 100% performed in our laboratory.
Actionable data, on-time, is our priority
Not all LC-MS CRO’s are equal. IQ Proteomics has the experience, the personnel, and the instrumentation, to provide on-time confident, accurate, and precise quantitative proteomics data. Please learn more through our reference material.