NEXT-GENERATION PROTEOMIC APPLICATIONS

Optimized workflows for comprehensive and on-time proteome characterization

Unbiased, proteome-wide, quantitative proteomics

  • Wide variety of biological matrices, including cell lines, primary tissues, and biofluids (serum, plasma, csf)
  • Drug target identification and specificity profiling
  • Chemoproteomics
    • Unbiased covalent inhibitor target profiling
    • Target engagement
  • Quantitative protein-protein interactions profiling (immunoaffinity purification, proximity labeling)
  • Post-translational modifications 

Technology

  • Multiplexing with TMT™ 18-plex reagents
  • PTMScan® Technology (phosphotyrosine, acetylation, ubiquitylation)
  • Real-time search MS3 (TMT™) or DIA acquisition
    • Orbitrap Lumos/Eclipse
    • Orbitrap Exploris 480
    • Orbitrap Astral
  • Dedicated informatics pipeline for data analysis

Consistent, sensitive, and rapid quantification of biologically relevant targets

  • Custom targeted assays
  • Target engagement
  • Absolute and relative quantification
  • Reduced sample requirements and high-throughput sample analysis

Technology

  • PRM or multiplexed (TMT™) assays
    • Orbitrap Lumos/Eclipse/Exploris
    • Orbtirap Astral
  • End-to-end automated plate-based sample preparation
  • Preferred vendors for isotopically heavy standards

Support services for proteome characterization

  • Cell culture
  • Proteome informatics
  • Instruments as a Service
    • LC-MS acquisition of customer prepared samples (hourly / weekly / monthly pricing)
  • Expedited processing / data acquisition

Technology

  • Scalable local and cloud computing
  • Automated sample preparation
  •  BSL2 certification

Why IQ Proteomics

Proven expertise

Established in 2015, IQP’s leadership has a proteomics specific background and extensive training in proteomics, including a library of peer-reviewed publications. IQP has completed thousands of projects from nearly all of the world’s largest, to the newest, pharmaceutical and biotechnology companies.

Dedicated facilities

Located just outside of Boston, MA, IQP occupies a purpose-built LC-MS laboratory for sample storage, preparation, LC-MS analysis, and cell culture.  All work is 100% performed in our laboratory.  

Actionable data, on-time, is our priority

Not all LC-MS CRO’s are equal.  IQ Proteomics has the experience, the personnel, and the instrumentation, to provide on-time confident, accurate, and precise quantitative proteomics data.  Please learn more through our reference material.

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