Eribulin Induction of Immunogenic Cell Death (ICD):Comparison With Other Cytotoxic Agents and Temporal Relationship of ICD Biomarkers

Preclinical studies were undertaken to investigate whether eribulin’s known cytotoxic antimitotic effects are characterized by immunogenic cell death (ICD) as assessed by three established ICD biomarkers: extracellular released ATP, released HMGB1 and cell surface calreticulin.

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